ECVAM, ECETOC and the EU Chemicals Policy. Alternatives to animal experiments: Progress made and challenges ahead. The proceedings of the ECVAM Status Seminar 2002, held on 4-6 June 2002, in the amphitheatre at the European Commission Joint Research Centr
2002
ATLA Alternatives to laboratory animals 2002 ;30 (SUP2):185-187 | Syngenta Central Toxicology Laboratory, Alderley Park, Macclesfield, Cheshire, SK10 4TJ, United Kingdom
Refinement of the Episkin protocol for the assessment of acute skin irritation of chemicals: follow-up to the ECVAM prevalidation study
2002
Toxicol In Vitro 2002 Dec ;16 (6):765-70 | L'Oreal Recherche, Aulnay sous Bois, France. [email protected]
The use of standardized human skin models for cutaneous pharmacotoxicology studies
2002
Skin Pharmacol Appl Skin Physiol 2002 ;15 Suppl 1):1-3 | L'Oreal, Life Sciences, Advanced Research Laboratories, Clichy, France. [email protected]
Characterization of reconstructed skin models
2002
Skin Pharmacol Appl Skin Physiol 2002 ;15 (Suppl 1):4-17 | Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands. [email protected]
Improvement of the experimental setup to assess cutaneous bioavailability on human skin models: dynamic protocol
2002
Skin Pharmacol Appl Skin Physiol 2002 ;15 Suppl 1():31-39 | L'Oreal Research, Aulnay-sous-Bois, France. [email protected]
ECVAM's research and validation activities in the fields of topical toxicity and human studies
2002
Altern Lab Anim 2002 Dec ;30 Suppl 2):119-23 | ECVAM, Institute for Health & Consumer Protection, European Commission Joint Research Centre, 21020 Ispra (VA), Italy.
A prevalidation study on in vitro tests for acute skin irritation. results and evaluation by the Management Team
2001
Toxicol In Vitro 2001 Feb ;15 (1):57-93 | Unilever Research, Colworth House, Sharnbrook, Bedfordshire MK44 1LQ, UK. [email protected]
Generation of oxidative stress in human cutaneous models following in vitro ozone exposure
2001
Toxicol In Vitro 2001 Aug-Oct ;15 (4-5):357-62 | L'OREAL Advanced Research, Life Sciences Division, 93600 Aulnay Sous Bois, France. [email protected]
Use of a standardized reconstructed epidermis kit to assess in vitro the tolerance and the efficacy of cosmetics
2000
In vitro and molecular toxicology 2000 ;22 (6):409-419 | L'Oreal Life Science Research, 90 rue du general Roguet, 92583 Clichy, France; Episkin SNC ZI des Trocques, 69630 Chaponost, France
Comparison of surface free energy between reconstructed human epidermis and in situ human skin
2000
Skin Res Technol 2000 Nov ;6 (4):245-249 | L'Oreal, Applied Research and Development, Microbiology Department, Chevilly-Larue; L'Oreal, Advanced Research Centre, Life Sciences, Aulnay-sous-bois; INRA, Bioadhesion and Material Hygiene Research Unit, Massy, France.
Covalently bound lipids in reconstructed human epithelia
2000
Acta Derm Venereol 2000 Mar-Apr ;80 (2):89-93 | Department of Dermatology, Leiden University Medical Center, The Netherlands. [email protected]
Lipid and ultrastructural characterization of reconstructed skin models
2000
Int J Pharm 2000 Aug 10 ;203(1-2):211-225 | Sylvius Laboratory, Department of Dermatology, Leiden University Medical Center, P.O. Box 9503, 2300 RA, Leiden, The Netherlands. [email protected]
Characterization and comparison of reconstructed skin models: morphological and immunohistochemical evaluation
2000
Acta Derm Venereol. 2000 Mar-Apr;80(2):82-8. | Department of Dermatology, Leiden University Medical Center, The Netherlands
Exogenous sphinganin derived sphingolipid increases epidermal ceramide content in human reconstructed skin
1999
Nouvelles Dermatologiques 1999 ;18 (8):541-546 | I. Castiel-Higounenc, Life Sci. Adv. Res. Ctr. C. Zviak, 90, rue du General Roguet, 92583 Clichy Cedex
Selective induction of interleukin-12 in reconstructed human epidermis by chemical allergens
1999
International journal of cosmetic science 1999 ;27 (2):261-269 | Center for Cosmetic Toxicology, Institute of Pharmacological Sciences, Via Balzaretti 9, 20133 Milan, Italy; Laboratoire de Recherche Fondamentale de L'Oreal, 93600 Aulnay-sous-Bois, France
Potential cosmetic applications of reconstructed epidermis
1999
Toxicology in vitro 1999 ;21 (1):51-58 | L'Oreal, Centre Charles ZVIAK, Life Science Research, 90 rue du General Roguet, 92583 Clichy, France
Industry experience with alternative methods
1998
Toxicol Lett 1998 Dec 28 ;102-103):575-9 | Life Sciences-L'OREAL Advanced Research, Clichy, France.
Reconstructed skin for in vitro cutaneous pharmacotoxicology: Example of metabolic studies
1997
IN VITRO TOXICOL J MOL CELL TOXICOL. In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1997 ;10 (1):3-9 | R. Roguet, Life Sciences, L'Oreal Advanced Res. Laboratories, 1 Avenue E. Schueller, 93600 Aulnay sous Bois
Overview of in vitro cell culture technologies and pharmaco-toxicological applications
1997
Toxicology in vitro 1997 ;11 (5):591-599 | L'Oreal, Advanced Research, Life Sciences Research. I av. E. Schueller, 93601, Aulnay sous bois, France; Laboratoire de Cytophysiologie et Toxicologie Cellulaire, Universite Paris VII Denis Diderot, Tour 53/54 E3, 2 Place Jussieu, 75251 Paris, France; Sch
The use of a reconstructed epidermis in the assessment of cytotoxic effects of UV irradiation
1996
Nouvelles Dermatologiques 1996 ;15 (5):384-389 | L'Oreal Recherche, Direction des Sciences du Vivant, Avenue E. Schueller,93600 Aulnay sous Bois