Protective effects of Polypodium leucotomos extract against UVB-induced damage in a model of reconstructed human epidermis

Polypodium leucotomos (PL) exerts potent antioxidant, photo-protective,

and immune-modulatory activities. A reconstructed human epidermis (RHE) (Episkin) is a suitable model for the evaluation of acute UV-induced cell damage. No data regarding the photo-protective action of PL in this model are available.

In vitro test approach

2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd
Laboratory of Biocompatibility Innovative Technologies and Advanced Therapies (BITTA), Rizzoli Orthopaedic Institute. Dermatology Clinic of the University of Bolgna. Medical Direction Difa Cooper, Caronno Pertusella, Italy.