AUTHORS : Alepee N. Cotovio J Grandidier MH Lelièvre D Meunier Jean-Roch Tornier C MODELS : EPISKIN RHE / RECONSTRUCTED HUMAN EPIDERMIS APPLICATIONS : SKIN IRRITATION OF CHEMICALS Evaluation of the in vitro EpiSkin and SkinEthic RHE Skin Irritation test methods for hazard identification of chemicals 2011 |
AUTHORS : Alepee N. Blond S. Cotovio J Duché Daniel Eilstein Joan Grandidier MH Meunier Jean-Roch MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : OCULAR IRRITATION OF CHEMICAL In vitro Assessment of Eye Tolerance using the SkinEthic HCE Test Method Applied to Ingredients Used in Cosmetic 2011 | L'Oreal
AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier MH Leclaire J Lee AV Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle MODELS : HCE / HUMAN CORNEAL EPITHELIUM APPLICATIONS : Eye irritation OCULAR IRRITATION OF CHEMICAL In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic HCE model: application to 435 substances from consumer products industry. 2010 Toxicology In Vitro. 2010 Mar;24(2):523-37. | L'Oréal, Research & Innovation
AUTHORS : Alepee N. Amsellem Carole Bertino Beatrice Bremond Christelle Capallere Christophe Cotovio J de Brugerolle de Fraissinette A. Grandidier M H Leclaire J Lelièvre D Loisel-Joubert Sophie Maloug Saber Meunier Jean-Roch Minondo Anne-Marie Ovigne Jean-Marc Tinois-Tessonneaud Estelle Van Der Lee Aline MODELS : HCE / HUMAN CORNEAL EPITHELIUM In vitro assessment of eye irritancy using the Reconstructed Human Corneal Epithelial SkinEthic™ HCE model: Application to 435 substances from consumer products industry 2009 | SkinEthic
AUTHORS : Bonaventure N. Christiaens F Cotovio J Coutet J Justine P Lelièvre D Marrot L MODELS : EPISKIN APPLICATIONS : Phototoxicity The episkin phototoxicity assay (EPA): Development of an in vitro tiered strategy using 17 reference chemicals to predict phototoxic potency 2007 Toxicol In vitro, 2007 Sep;21(6):977-995 | L'Oreal Research, Life Sciences, 1 Av. E. Schueller,93600 Aulnay-sous-Bois
AUTHORS : Botham P A Cotovio J Curren R Fentem JH Gamer AO Gerner I Heylings J R Kandarova H Liebsch M Remmele M Roguet R Spielmann H Worth AP Zuang V MODELS : EPISKIN APPLICATIONS : SKIN IRRITATION OF CHEMICALS The ECVAM international validation study on in vitro tests for acute skin irritation: report on the validity of the EPISKIN and EpiDerm assays and on the Skin Integrity Function Test. 2007 | Episkin
AUTHORS : Catroux P Cotovio J Justine P Lamure S Onno L MODELS : EPISKIN Generation of oxidative stress in human cutaneous models following in vitro ozone exposure 2001 Toxicol In Vitro 2001 Aug-Oct ;15 (4-5):357-62 | L'OREAL Advanced Research, Life Sciences Division, 93600 Aulnay Sous Bois, France. [email protected]
AUTHORS : Cotovio J Leclaire J Roguet R MODELS : EPISKIN APPLICATIONS : PHARMACOLOGY / TOXICOLOGY SKIN METABOLISM Reconstructed skin for in vitro cutaneous pharmacotoxicology: Example of metabolic studies 1997 IN VITRO TOXICOL J MOL CELL TOXICOL. In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1997 ;10 (1):3-9 | R. Roguet, Life Sciences, L'Oreal Advanced Res. Laboratories, 1 Avenue E. Schueller, 93600 Aulnay sous Bois
AUTHORS : Cotovio J Leclaire J Pion F X Roguet R Rougier A MODELS : EPISKIN Effect of imidazole derivatives on cytochrome P-450 enzyme activities in a reconstructed human epidermis 1996 Skin Pharmacol 1996 ;9 (4):242-9 | L'OREAL Advanced Research Center, Aulnay-sous-Bois, France.
AUTHORS : Cotovio J Kremers P Leclaire J Pouradier Duteil X Roguet R Rougier A MODELS : EPISKIN APPLICATIONS : SKIN METABOLISM Cytochrome P450-dependent enzyme activities and testosterone metabolism in a reconstituted human epidermis 1995 In Vitro Toxicology: Journal of Molecular and Cellular Toxicology 1995 ;8 (1):97-104 | L'Oreal, Dept Central Securite Produits, 1, Avenue Eugene Schueller,93600 Aulnay sous Bois