EPISKIN Academy at the National Conference on Alternatives to Animal Experiments




EPISKIN Academy is invited to give a talk and a pre-conference training to the National Conference on Alternatives to Animal Experiments (NCAAE-2018) that will be held December 1st 2018 in New Delhi (India).


The Conference will be held at Jamia Hamdard, New Delhi, a Deemed to be University accredited in category ‘A’ by the National Assessment and Accreditation Council of India.
This Conference aims to discuss the perspectives on the current state of practices and existing strategies to promote the development of non-animal technologies in India (


On November 26th, Jamia Hamdard in collaboration with EPISKIN Academy under the aegis of Indian Society for Alternatives to Animal, organize a Hands-on Workshop to train 20 young scientists on Alternatives and in vitro skin Irritation according to OECD TG-439.




EPISKIN at the Eurofins Human Safety Seminar

In Vitro Toxicology at a Glance: Today's Challenges, Solutions & Future Developments



EPISKIN is invited to give a lecture at the Eurofins Human Safety Seminar.


The Seminar will take place on November 29th, 2018 in the new laboratory and office building of Eurofins Munich, Robert-Koch-Straße 3a in Planegg near Munich, Germany. 


Dr Pellevoisin, scientific director of EPISKIN Academy will give an overview of eye irritation methods with a focus on OECD TG492 for eye irritation of chemicals in the context of the Guidance Document on an Integrated Approach on Testing and Assessment (IATA) for Serious Eye Damage and Eye Irritation.


The second part of the talk will address the last advancement in skin sensitization testing strategies and added values of reconstructed human epidermis for this endpoint.


Follow this link to learn more about the Eurofins Seminar.



ESTIV 2018 20th International Congress on In Vitro Toxicology

 The 20th International Congress on In Vitro Toxicology will be presented from October 15th in Berlin, Germany.


Come and discover the new EPISKIN Academy presentation during the ESTIV congress:


Thursday, ocotber 18th

09.18 (OP 32): 

Reconstructed human epithelia for in vitro biocompatibility of medical devices
Pellevoisin Christian (Lyon/FR) 


To discover full programme please visit the ESTIV website.




The EPISKIN Academy at the IID 2018



During last IID (International Investigative Dermatology) congress which was held from May 16th to 18th, in Rosen Shingle Creek Resort, Orlando, Florida, the EPISKIN Academy presented two posters about the EPISKIN models:


01156 T-SKIN, a new industrial reconstructed human skin model for dermatological and cosmetics research and development

C. Pellevoisin, D. Lelièvre, M. Bataillon, N. Boyera, A. Rigaudeau, J. Ovigne, I. Besné, N. Seyler

Journal of Investigative Dermatology, Vol. 138, Issue 5, S196

Published in issue: May 2018



01085 Cellular mechanistic investigation on antigen delivery by Viaskin® patch for epicutaneous immunotherapy with reconstructed human epidermis including Langerhans cells (SkinEthicTM RHE-LC)

V. Dioszeghy, C. Pellevoisin, M. Ligouis, F. Sahuc, V. Dhelft, L. Mondoulet

Journal of Investigative Dermatology, Vol. 138, Issue 5, S184

Published in issue: May 2018







EPISKIN ACADEMY poster reward at the 57th SOT




The EPISKIN Academy has been honored by receiving the Best Overall Abstract Award for its poster in Medical Device and combination product speciality section (MDCPSS) presented during the 57th SOT meeting and ToxExpo, in San Antonio, Texas, USA.


This poster is the result of a collaboration between ImmunoSearch, Medtronic and the EPISKIN Academy. It has been written by 3 co-authors: Kelly Coleman (Medtronic), Hervé Groux (ImmunoSearch) and Christian Pellevoisin (EPISKIN Academy).


C. Pellevoisin (EPISKIN Academy), K. Coleman (Medtronic), H. Groux (ImmunoSearch)

C. Pellevoisin (EPISKIN Academy), K. Coleman (Medtronic), H. Groux (ImmunoSearch)




Workshop EPISKIN Academy in India

Workshop & training session in India


The firth edition of the MGDC-EPISKIN Academy will be held in Mumbai on December 15th-19th.


This 2017 edition, welcomed by the National Facility for Biopharmaceuticals (NFB), coincides with the “1st NATIONAL CONGRESS ON ALTERNATIVES TO ANIMAL TESTING”, a one day conferences co-organized by NFB and EnvisBE.

Because of the recent release of the OECD test guideline 492 for eye irritation, EPISKIN Academy will deliver training 2 sessions: One for Skin irritation according to OECD TG439 and the second for eye irritation according to OECD TG 492.


To learn more about the workshop and training sessions please read the following document:

1st National Congress on Alternatives to Animal Testing - NFB - EPISKIN Academy



To subscribe to the training sessions please use the form below:

REGISTRATION FORM Conference Workshop Alternative Methods





Workshop on 3Rs in Turkey


For the first time EPISKIN Academy will train Turkish scientists to OECD TG439 for in vitro skin irritation of chemicals. This event is co-organized by the TÜBİTAK Marmara Research Center and the CAAT Academy.

EPISKIN Academy in collaboration  with local partners share expertise and train young and confirmed scientists to face alternative to animal testing challenges.

3Rs & 2D and 3D Liver, Skin, Eye and Intestinal Regulatory Models. This event is scheduled on November 2 and 3, 2017, at TUBITAK MAM, Gebze - Kocaeli, Turkey. 


To learn more about the workshop please follow this link:






Training Session in Rio de Janeiro, Brazil


The first EPISKIN Academy training session in Brazil held in Rio de Janeiro from May 16th to the 17th. It followed the Tissue Engineering day organized by L'Oréal which brought together more than hundred scientists from industry, academics, and governental organizations to discuss the future of this scientific field in Brazil.


During these two days of the training, 8 Brazilian scientists from governmental institutions and industry have been trained to the OECD test guideline 439 for in vitro skin irritation of chemicals with reconstructed human epidermis. This session was hosted by laboratories of the National Institute for Metrology, Quality and Technology (INMETRO). The OECD TG439 is one of the 17 validated alternative methods recommended by the Brazilian Center for Validation of Alternative Methods (BraCVAM) and recognized by the National Council for the Control of Animal Experimentation (CONCEA) to address the ban of animal testing which will enter into force in Brazil in 2019. The training alternated lectures and hand-on sessions to give both theoretical and practical knowledge to implement and use the results of the TG439. The laboratory session put the trainees in a real situation to assess skin irritation potential of 2 unknown products compared to negative and positive controls with reconstructed tissues, SkinEthic™ RHE tissues, produced in Brazil. The final part of the session has been dedicated to the interpretation and discussion of the experimental results and to certification of the trainees.

Brazil is the third country, after France and China, to produce locally an EPISKIN model. The SkinEthic RHETM model, used during the training, is produced through collaboration between L'Oréal and the Brazilian D'Or Institute for Research and Education (IDOR). EPISKIN, world leader of reconstructed human tissues for 25 years developed a wide range of expertise of applications of these models in different scientific, technological and regulatory contexts for both safety and efficacy purposes. In 2012, EPISKIN Academy have been created to share this knowledge and to prepare next generation of stakeholders to face the challenge of 21st century toxicology. EPISKIN Academy promotes and trains scientists all over the world to alternatives to animal testing in toxicology. To date more than 300 scientists have been trained in Europe, ASIA and America.


To view the video please follow this link: EPISKIN Academy Training Session in Brazil




SkinEthic Reconstructed Epidermis Model

 Inexo Symposium 2017 on Alternative Models


On July 7th, 2017 in Montpellier, France, the EPISKIN Academy will attend the Inexo Symposium 2017 on Alternative Models "in vitro, Ex ovo et Organismes": De la recherche aux applications dans les pathologies et le vieillissement.

Don't miss the EPISKIN ACADEMY presentation about Reconstructed Skin ("Peaux reconstruites") at  Amphi B by Dr. Christian Pellevoisin.

To discover the complete scientific program please follow this link:





8th World Congress on Toxicology and Pharmacology


On April 13-15, 2017 in Dubai, UAE, the EPISKIN Academy will attend the 8th Congress on Toxicology and Pharmacology.

Don't miss our keynote session on April, 15th, 2017 that will be held from 09:30 to 10:20: Reconstructed skin models and methods for hazard and risk assessment of chemicals and cosmetics presented byChristian Pellevoisin,

To discover the complete scientific program please follow this link:








The Episkin Academy will attend the SID 2016 Annual Meeting that will be held at the Westin Kierland Resort & Spa in Scottsdale, Arizona, from May 11 to 14, 2016.

'The use of SkinEthic reconstructed human epidermis (RHE) to study immunocompetent cells trafficking and recruitment between skin compartments' will be presented during poster session on Thursday, May 12 and Saturday, May 14.

To learn more about SID annual meeting and scientific program, please follow this link:



 Episkin Academy China


EPISKIN Academy created in China



L'Oreal China and Shanghai EPISKIN Biotechnology Ltd. announced the creation of the EPISKIN Academy in China.
Through training and technical collaborations, the Academy will work with Chinese scientists, key opinion leaders, students and future stakeholders in terms of scientific and regulatory issues for alternatives to animal testing in field of safety, toxicology and efficacy as well as in other relevant areas.

To further promote the reconstructed skin models through marketing, L'Oréal China and EPISKIN SA created Shanghai EPISKIN Biotechnology Ltd. in 2014 to produce reconstructed skin models according to high quality standards in the industry. The models will be used primarily for research on skin tissue engineering and testing. This time the creation of the EPISKIN Academy will certainly play an important role in promoting in vitro skin models in the industry.

"In China, the Academy will work closely with various parties to promote the reconstructed skin models and alternative methods in China, and will strive to become a key scientific resource to further stimulate innovation in the Chinese cosmetics industry" said Dr. Christian Pellevoisin, scientific Director of the EPISKIN Academy.



The Episkin Academy at CIFARP

The Episkin Academy at CIFARP

Dr Christian Pellevoisin, Scientific Director of the Episkin Academy, has been invited by the Organizing Committee of CIFARP to be a speaker at 10th Congress of Pharmaceutical Sciences that will be held in Ribeirão Preto – São Paulo -Brazil, from September 06-09, 2015.

This year the theme is “Translating science into health pipeline” : 

September 8th - 10:30-12:30 - S9.2: Episkin and the application of reconstructed human 3D models in toxicology and pharmacology.

CIFARP 2015 will be a unique opportunity to discuss the latest trends and scientific breakthroughs in the pharmaceutical sciences field. About 1400 national and international participants are expected, including researchers, professionals, as well as postgraduate and undergraduate students. 

For more information consult the website of the congress:



New Dedicated Training sessions are coming...

Episkin Academy training: ENMV Sidi Thabet- Tunisia, february 23-26, 2015

The National School of Veterinary Medicine Sidi Thabet organized a training in animal experiments which  theme was: "From in vivo models to cell models".

This training took place in ENMV of Sidi Thabet (University of Manouba) and lasted 4 days from 23 to 26 February 2015.

34 participants (biology doctoral students, teacher-researchers, veterinarians, industrial and control pharmacists) were informed of the new cell technologies and alternative methods which aim to replace animals in drug-Toxicological, chemical and cosmetics testing. Practical workshops and round table helped to promote exchanges and networking with European partners.

Main objectives:

  • Promote good practice and ethics in animal experimentation based on the principle of the 3Rs (Replacement, Reduction, Refinement).
  • Presentation and training on new cellular technologies (2D and 3D) on two organs: liver and skin (primary liver cells, liver microsome, skin cells ...) in the pharmaco-toxicological and pharmaceutical research.
  • Present the situation in Europe and internationally of the new technologies (in silico, in vitro, omics "adverse outcome pathways") in the academic and regulatory (REACH) context.

This training also offers an opportunity to discuss collaborative projects (medium and long term) with the scientific and medical community as well the pharmaceutical industry in the new research program called European "Horizon 2020" and beyond.

The Episkin Academy presented the Pharmacotoxicology applications of the 3D reconstructed human epidermis models during the round table. This presentation was followed by a training session on the use of our epidermal tissues.


Scientific Program:

9h00 – 12h00 14h00 – 17h00
Feb 23, 2015
- Welcome and registration
- Ethics and Welfare AL
- Guiding principles CIOMS / ICLAS
- Recommendations of the OIE (OIE)
(Ouajdi Souilem, ENMV Sidi Thabet)
Workshop 1
Demonstrations on in vivomodels
Team Azal / ENMV / IPT
Feb 24, 2015
- Place of alternative methods in EA
(Sarrah M'barek, ISSBAT, Tunis)
-Internationally trendof the 3Rs and funding opportunities
(FrançoisBusquet coordinator CAAT, EU, Belgium)
- Zebrafish Model and Applications
(François Busquet, EU Brussels)
Workshop 2
REACH and MA Dissemination in Tunisia
Intervention of the Chemistry technical center
Setting up a test platform (François Busquet)
Feb 25, 2015
- Cell culture: advantages and limits
(Olfa Masmoudi, FST, Tunis)
- In vitro toxicology - pharmacology
(Christophe Chesné, France)
- Applications in pharmacotoxicology of 3D reconstructed human epidermal models
(Christian Pellevoisin, France)
Workshop 3
2D models: liver cells
HepaRG BIOPREDIC (Christophe Chesné)
Feb 26, 2015
Workshop 4
3D models: skin cell culture
Episkin Academy - Lyon (Christian Pellevoisin)
Synthesis, debate and Discussion
Distribution of certificates
Closing Ceremony


Workshop & training session in India


Workshop & training session in India